Epiphyseal cartilage from a young C57BL/6 mouse before (left) and after (right) sampling using laser-capture microdissection. LCM is an...

Formation of multinucleated osteoclast-like cells in culture requires the addition of RANKL (receptor activator of NFkB ligand), a...

Humeral head, juvenile dog, experimental oral administration of fluoroquinolone antibiotic. Chondropathy secondary to administration of...

Young dog. Cross-section through the distal femoral metaphysis. Osteochondroma is a developmental anomaly (at least in dogs) that...

A simple illustration of bone's adaptability according to Wolff's theories. Keep in mind, Wolff was only working with gross specimens of...

Julius Wolff was a 19th century surgeon who famously described the relationship between bone shape/form and function/mechanics. His...

Experimental cancer model showing tibial intramedullary prostate carcinoma growth. The bone response to tumor cells can be as...

Contrast-enhanced, ventral-dorsal radiograph of an adult, male budgerigar (parakeet-type bird) illustrating the difference in x-ray...

Stifle joint, anterior (cranial), 10-week-old mouse (athymic). A few months have passed in our previously 1-day-old mouse, and the...

Stifle joint, anterior (cranial), 1-day-old mouse (C57BL/6). The meniscus is a specialized fibrocartilaginous structure of the stifle...

Metaphyseal side of physis, 1-day-old mouse (C57BL/6), nondecalcified section. The chondroclast (red circle) is a multinucleated cell...

Metaphyseal side of the physis, 1-day-old mouse (C57BL/6), nondecalcified section. Three events are necessary for orderly endochondral...